White House Hotel

CITY GUIDES | THE SOUTH

The Best Mississippi Hotels, From Delta Stays to Gulf Coast Resorts

By Rebecca Thompson | April 3, 2026


AUTHOR BIO: Rebecca Thompson has held many jobs over the years, from daily newspaper writer to middle-school math teacher. As a restaurant critic, she’s reviewed Michelin-starred fine-dining to gas station barbecue.

Kelly McMurtry The Adventurist

I end up in Mississippi for work more months than not, drifting across the state for tasks somebody put on my calendar and the sort of long drive that gives a person entirely too much time to think. And each time, I find myself playing the same private little game: perhaps this will be the trip when I come upon a hotel grand enough to unseat my current favorite, a place with enough character to justify my continued refusal to spend the night in some chain box beside the interstate.

Because Mississippi does have its darling hotels, though not always in the places the tourism brochures would have you expect. Some are polished and properly Southern, some are strange in the loveliest ways, and some are old enough to understand that charm has less to do with perfection than with knowing which rough edges ought to be left alone.

So until the next trip rearranges the order, these are my current favorites, the best hotels in Mississippi.


The Alluvian Hotel and Spa Mississippi Best Hotels

The Alluvian Hotel, Greenwood

$$$$$ | MAP | WEBSITE | INSTAGRAM

The Alluvian is a 45-room hotel in downtown Greenwood with five suites, four lofts, a 7,000-square-foot spa, and one of the better built-in food setups of any hotel in the state. Giardina’s is tied into the property, the Viking Cooking School is right there, and the spa leans into Delta-coded treatments like its sweet tea service. This is the Mississippi Delta version of doing a hotel weekend properly, where I’ll check in once and not need to go elsewhere.

Best for: A polished Delta weekend


Beau Rivage Resort & Casino Biloxi Mississippi Best Hotels

Beau Rivage Resort & Casino, Biloxi

$$$$$ | MAP | WEBSITE | INSTAGRAM

Beau Rivage is the Biloxi hotel for going big, with 1,740 rooms, 95 suites, a 24-hour casino, a long list of restaurants, and the kind of Gulf views that make even a slot-machine weekend look a little grander. Coraline’s does the local seafood-and-Cajun thing with a legit seafood gumbo, while Salt & Ivy covers coastal brunch and Southern standards under the atrium. It is a casino resort, yes, but it is also the Coast’s most fully realized hotel machine.

Best for: Full-throttle Biloxi


Fairview Inn Mississippi Best Hotels

Fairview Inn, Jackson

$$$$$ | MAP | WEBSITE | INSTAGRAM

Fairview Inn is set in a historic mansion in Jackson and has the scale that makes a place feel personal instead of transactional. The property has 18 rooms, a private spa, 1908 Provisions, and the Library Lounge downstairs, where the shelves are lined with Mississippi writers instead of generic hotel décor. It works because it gives Jackson something chain hotels never can: a stay with an actual point of view.

Best for: A real boutique stay in Jackson


Gulf Hills Hotel + Resort Mississippi Best Hotels

Gulf Hills Hotel + Resort, Ocean Springs

$$$$$ | MAP | WEBSITE | INSTAGRAM

Gulf Hills has the bones of an old coast resort and serves as Ocean Springs’ only waterfront hotel. That setup includes a pool, Sunset Lounge for drinks, and food options tied to the neighboring golf club, including Italy Terrace and Capone’s Speakeasy Lounge. It feels less like a newly manufactured boutique and more like a place that has been around long enough to know what works.

Best for: Old-school Coast atmosphere


Hotel Whiskey in Pass Christian Mississippi Best Hotels

Hotel Whiskey, Pass Christian

$$$$$ | MAP | WEBSITE | INSTAGRAM

Hotel Whiskey is a small boutique in Pass Christian with room types that stay simple—suite, upper king, lower king, queen—and a restaurant downstairs that gives the whole place its center of gravity. Whiskey Prime runs Thursday through Sunday, with happy hour starting at three and dinner at five, and the menu leans on steaks, fresh local seafood, and cocktails. The whole operation is compact and unfussy, which is part of why it works.

Best for: A quiet Coast overnight with dinner downstairs


The Inn on Whitworth Best Mississippi Hotels

The Inn on Whitworth, Brookhaven

$$$$$ | MAP | WEBSITE | INSTAGRAM

The Inn on Whitworth makes a strong case for why small-town boutique hotels can be far more interesting than branded luxury. The downtown Brookhaven building keeps its original heart-pine floors, a century-old skylight, and a Mesker metal façade, while the hotel itself mixes local art with seven rooms, seven suites with kitchens, and lofts that feel more residential than hotel-like. I like that there’s real texture here, the kind that comes from using the building instead of covering it up.

Best for: Small-town character with actual design sense


Lyric Hotel, Cleveland West End District Mississippi Best Hotels

Lyric Hotel, Cleveland

$$$$$ | MAP | WEBSITE | INSTAGRAM

Lyric Hotel is part of Cleveland’s West End District and has more scale than some of the smaller boutique places on this list. But it still gets the details right. The property has 63 rooms, including two executive king suites and three king parlors, plus a coffee bar in the lobby, lounge areas for live music, a central courtyard, a pool, and a lake with over-the-water entertainment decks. It is polished without pretending it’s in Paris.

Best for: A stylish Delta base


Monmouth Historic Inn & Gardens, Natchez Mississippi Best Hotels

Monmouth Historic Inn & Gardens, Natchez

$$$$$ | MAP | WEBSITE | INSTAGRAM

Monmouth is the Natchez classic: an 1818 mansion on 26 acres so serene I’ll find myself walking slower here without realizing it. The on-site Restaurant 1818 is run by Natchez native chef Jay Yates and serves dinner in what were originally the men’s and ladies’ parlors of the main house, beneath custom crystal gasoliers made by Waterford artisans. Plenty of historic inns trade on age alone; this one still has some theater to it.

Best for: The full Natchez mansion experience


Oliver Hotel of Oxford Mississippi Best Hotels

The Oliver Hotel, Oxford

$$$$$ | MAP | WEBSITE | INSTAGRAM

Maybe most folks visiting Oxford want to be nearer to campus, but The Oliver’s location just off the Square means it’s more of a destination for exploring this charming Southern city. The hotel has 40 rooms, the restaurant Kingswood for refined Southern cooking, and Nightbird, a moody little bar tucked inside the property for cocktails after dinner. A lot of Oxford hotels are really just places to sleep near campus; this one actually feels like part of town.

Best for: A polished Oxford weekend


The Roost Ocean Springs Mississippi Best Hotels

The Roost, Ocean Springs

$$$$$ | MAP | WEBSITE | INSTAGRAM

The Roost’s renovation did exactly what should happen with a historic building: it took all the great bones of the Porter House and simply improved it. The suites mix original elements from the building with custom furnishings, woodblock artwork by Walter Anderson, locally roasted coffee, and Aveda bath products. Even with all those changes, it still feels specific to Ocean Springs, and best of all, sunset walks on the beach are never far away.

Best for: Boutique coastal style without the beach-theme clichés


Travelers Hotel Clarksdale Mississippi Best Hotels

Travelers Hotel, Clarksdale

$$$$$ | MAP | WEBSITE | INSTAGRAM

Travelers Hotel is a 20-room, artist-run place in downtown Clarksdale, set in a restored building that once housed railroad workers. The rooms lean industrial, with exposed brick and concrete floors, and the hotel has become known for local art, a bar, and the deliberate absence of televisions in the rooms. That last part says a lot about the intention of this place, built to encourage getting out and experiencing Clarksdale.

Best for: A Clarksdale stay with a point of view


White House Hotel Biloxi Mississippi Best Hotels.

White House Hotel, Biloxi

$$$$$ | MAP | WEBSITE | INSTAGRAM

White House Hotel has one of the better comeback stories on the Coast. The beachfront property sat vacant for 30 years, survived Katrina, was restored in 2013 and 2014, and reopened with 76 rooms, Gulf views, and the big white-column façade that still makes it look like Biloxi dressed up for the evening. Some historic hotels feel preserved under glass; this one feels like it has begun its second act.

Best for: Historic Biloxi on the water


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